GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2275426 | 1 | rs6662641 | chr1:46571509 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6 | 3.55E-8 | Body mass index |
| THYM | cis | rs4660306 | 1 | rs6667191 | chr1:45982844 | CCDC163P | chr1:45960581-45965646:- | -0.86 | -14.78 | 2.3E-26 | Homocysteine levels |
| THYM | cis | rs2275426 | 1 | rs6668284 | chr1:46354510 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.85 | 7.1E-8 | Body mass index |
| THYM | cis | rs6696239 | 1 | rs6669236 | chr1:227813909 | DUSP5P | chr1:228780657-228788159:+ | -0.81 | -5.13 | 1.51E-6 | Height |
| THYM | cis | rs2275426 | 1 | rs6669522 | chr1:46397941 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6 | 3.55E-8 | Body mass index |
| THYM | cis | rs7552404 | 1 | rs6672180 | chr1:76123973 | ACADM | chr1:76190043-76229353:+ | 0.3 | 4.16 | 7.08E-5 | Blood metabolite levels;Acylcarnitine levels |
| THYM | cis | rs2275426 | 1 | rs6672898 | chr1:46290588 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.85 | 6.8E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs6675726 | chr1:46560643 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6 | 3.55E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs6675946 | chr1:46371774 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6 | 3.55E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs6677007 | chr1:46400590 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -6 | 3.55E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs6680380 | chr1:46300189 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.85 | 6.8E-8 | Body mass index |
| THYM | cis | rs6691624 | 1 | rs6691624 | chr1:19987783 | NBL1 | chr1:19923467-19984945:+ | -0.31 | -4.22 | 5.5E-5 | Morning vs. evening chronotype |
| THYM | cis | rs2275426 | 1 | rs6695809 | chr1:46285461 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.85 | 6.8E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs6700597 | chr1:46284246 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.85 | 6.8E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs6701614 | chr1:46309420 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.85 | 6.8E-8 | Body mass index |